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Transgender men can become pregnant while on testosterone, so if you remain sexually active with a non-transgender man, you should always use a method of birth control to prevent unwanted pregnancy. If you suspect you may have become pregnant, discontinue testosterone treatment and see your provider as soon as possible, as testosterone can. Transgender hormone therapy of the female-to-male (ftm) type, also known as transmasculine hormone therapy, is a form of hormone therapy and sex reassignment therapy which is used to change the secondary sexual characteristics of transgender people from feminine or androgynous to masculine. It is a type of transgender hormone therapy (another being male-to-female), and is predominantly used to. For transgendered individuals, the start of hormone therapy can be exciting and anxiety-provoking. Because a trans mans genetic gender does not match his brain gender, testosterone therapy is administered to help masculinize his body. When a man born female begins taking testosterone, he goes through something similar to male puberty. Testosterone replacement therapy is also used in transgender men to induce virilization and to reduce the appearance of feminizing characteristics. In transgender women, exogenous estrogen (the female sex hormone) is used to help develop more pronounced feminizing qualities along with anti-androgens to suppress masculine features. transgender hormone replacement therapy hrt guide 101 (oestrogen & testosterone) what are hormones? There are many different hormones produced in the body by a system of glands. These release hormones directly into the bloodstream so that they are carried all round the body. Unlike transgender women who need to use a testosterone blocker in order for gender-affirming hormone therapy to be effective, there is no need to block the production of estrogen when taking testosterone. Testosterone is a more biologically effective hormone, and it will induce changes when taken on its own. Gender-affirming hormone therapy in transgender patients follows similar principles to the treatment of postmenopausal women and hypogonadal men. It is safe if monitored appropriately and delivered with attention to the holistic care of the patient. Testosterone therapy is a cornerstone of medical treatment for transgender men who choose to undergo it. The goal of testosterone therapy is usually to achieve serum testosterone concentrations in the male reference range. Testosterone has several desired effects as well as undesired and unknown effects. The desired effects include increased facial and body hair, increased lean mass and.